دوره 5، شماره 2 - ( 4-1386 )                   جلد 5 شماره 2 صفحات 40-39 | برگشت به فهرست نسخه ها

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Hadinedoushan H, Ghafourzadeh M. A survey of anti-sperm antibodies in infertile couples. IJRM 2007; 5 (2) :39-40
URL: http://ijrm.ir/article-1-59-fa.html
A survey of anti-sperm antibodies in infertile couples. International Journal of Reproductive BioMedicine. 1386; 5 (2) :39-40

URL: http://ijrm.ir/article-1-59-fa.html


چکیده:   (2290 مشاهده)
The presence of anti-sperm antibodies (ASA) in semen or serum may impair sperm function leading to immunological infertility. The aim of this study was to investigate the presence of ASA on the surface of sperm and in circulating blood of infertile couples. In this cross sectional study, we studied 49 couples suffering from infertility for at least one year. Serum ASA (IgG and IgA classes) was examined by indirect SpermMAR test. Also, ASA (IgG and IgA classes) attached to the surface of spermatozoa were tested by direct SpermMAR method in ejaculates from infertile men. ASA were positive in 8% of semen samples (2% IgG, 4% IgA, 2% both IgG and IgA classes). Only in one woman, ASA of the IgG class was found in serum samples. The presence of ASA may impair fertilizing ability and is a serious factor which may prevent the success of various fertilization techniques. ASA assessment should be considered as an essential part of infertility management.
نوع مطالعه: Original Article |

فهرست منابع
1. Koide SS, Wang L, Kamada M. Antisperm antibodies associated with infertility: properties and encoding genes of target antigens. Proc Soc Exp Biol Med 2000; 224: 123-132. [DOI:10.1046/j.1525-1373.2000.22410.x]
2. Mónica H, Vazquez-Levin D, Judith A, Notrica M, Ester Polak de Fried M. Male immunologic infertility: Sperm performance on in vitro fertilization. Fertil Steril 1997; 68: 675-681. [DOI:10.1016/S0015-0282(97)00255-0]
3. Fábio F, Antônio M, Lucon H, Plínio M, Góes B, Saldanha S. Induction of spermatogenesis in azoospermic men after varicocele repair. Hum Reprod 2003; 18: 108-112. [DOI:10.1093/humrep/deg032]
4. Clarke GN, Elliot PJ, Smaila C. Detection of sperm antibodies in semen using the immunobead test; a survey of 813 consecutive patients. Am J Reprod Immunol 1985; 7: 118-123. [DOI:10.1111/j.1600-0897.1985.tb00269.x]
5. Cesaro M, Valenti M, Massaccesi A. Correlation between the direct IgG MAR test (mixed antiglobulin reaction test) and seminal analysis in men from infertile couples. Fertil Steril 1985; 44: 390-395. [DOI:10.1016/S0015-0282(16)48865-5]
6. Haas GG, Schreiber AD, Blasco R. The incidence of sperm associated immunoglobulin and C3, the third component of complement, in infertile men. Fertil Steril 1983; 39: 542-547. [DOI:10.1016/S0015-0282(16)46948-7]
7. Marzena K, Alina D, Maciej K. The frequency of antisperm antibodies in infertile couples. Med Sci Monit 2003; 9: 194-201.
8. Busacca M, Fusi F, Brigante C. Evaluation of antisperm antibodies in infertile couples with immunobead test: prevalence and prognostic value. Acta Eur Fertil 1989; 20: 77-82.
9. Collins JA, Burrows EA, Yeo J, Young-Lai EV. Frequency and predictive value of antisperm antibodies among infertile couples. Hum Reprod 1993; 8: 592-598. [DOI:10.1093/oxfordjournals.humrep.a138102]
10. Bronson RA, Fusi F. Sperm-oolemmal interaction: role of the Arg-Gly-Asp (RGD) adhesion peptide. Fertil Steril 1990; 54: 527-529. [DOI:10.1016/S0015-0282(16)53775-3]
11. Lombardo F, Gandini L, Dondero F, Lenzi A. Antisperm immunity in natural and assisted reproduction. Hum Reprod Update 2001; 7: 450-456. [DOI:10.1093/humupd/7.5.450]
12. Nagy ZP,Verheyen G, Liu J, Joris H, Janssenswillen C, Wisanto A, et al. Results of 55 intracytoplasmic sperm injection cycles in the treatment of male-immunological infertility. Hum Reprod 1995; 10: 1775-1780. [DOI:10.1093/oxfordjournals.humrep.a136172]
13. Lombardo F, Gandini L, Lenzi A, Dondero F. Antisperm immunity in assisted reproduction. J of Reprod Immunol 2004; 62: 101-109. [DOI:10.1016/j.jri.2003.08.005]

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