Volume 13, Issue 3 (3-2015)                   IJRM 2015, 13(3): 149-154 | Back to browse issues page

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Amooee S, Gharib M, Ravanfar P. Comparison of anti-mullerian hormone level in non-endometriotic benign ovarian cyst before and after laparoscopic cystectomy. IJRM 2015; 13 (3) :149-154
URL: http://ijrm.ir/article-1-628-en.html
Comparison of anti-mullerian hormone level in non-endometriotic benign ovarian cyst before and after laparoscopic cystectomy
Sedigheh Amooee1 , Mahboubeh Gharib1 , Parsa Ravanfar * 2
1- Department of Obstetrics and Gynecology, Shahid Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
2- Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran , ravanfarpa@yahoo.com
Abstract:   (2431 Views)
Background: Benign ovarian cysts are common among both pre- and postmenstrual women. Surgical intervention for excision of an ovarian cyst is mandated when symptomatic, or chance for malignancy is high. The damaging effect of surgical ovarian cystectomy on ovarian reserve is debated in recent studies.
Objective: In the present study we investigated serum level of anti-mullerian hormone (AMH) as an indicator of ovarian reserve before and after surgical cystectomy.
Materials and Methods: 60 patients with dermoid cyst, serous cystadenoma, and mucinous cystadenoma were recruited. Measurement of serum AMH was performed prior to surgery, and at one and 3 months after laparoscopic cystectomy. Serum AMH levels were compared before and after the surgery and between various types of ovarian cyst.
Results: Serum AMH level declined significantly after the surgery which recovered to 65% of its baseline value three months later.
Conclusion: Decreased serum AMH can be contributed to decreased ovarian reserve after laparoscopic ovarian cystectomy. This can result from thermo-coagulation used for hemostasis during the operation.
Keywords: Dermoid cyst, Ovarian cyst, Anti-mullerian hormone, Cystadenoma, Mucinous, Serous.
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Type of Study: Original Article |
References
1. Valentin L, Skoog L, Epstein E. Frequency and type of adnexal lesions in autopsy material from postmenopausal women: ultrasound study with histological correlation. Ultrasound Obstet Gynecol 2003; 22: 284-289. [DOI:10.1002/uog.212]
2. Bottomley C, Bourne T. Diagnosis and management of ovarian cyst accidents. Best Pract Res Clin Obstet Gynaecol 2009; 23: 711-724. [DOI:10.1016/j.bpobgyn.2009.02.001]
3. Drake J. Diagnosis and management of the adnexal mass. Am Fam Physician 1998; 57: 2471-2480.
4. Audebert AJ. Laparoscopic surgery for ovarian cysts. Curr Opin Obstet Gynecol 1996; 8: 261-265. [DOI:10.1097/00001703-199608000-00005]
5. Thornton KL, DeCherney AH. Laparoscopic management of ovarian cysts: an endocrinologist view. Yale J Biol Med 1991; 64: 599-606.
6. Yuen PM, Yu KM, Yip SK, Lau WC, Rogers MS, Chang A. A randomized prospective study of laparoscopy and laparotomy in the management of benign ovarian masses. Am J Obstet Gynecol 1997; 177: 109-114. [DOI:10.1016/S0002-9378(97)70447-2]
7. Chang HJ, Han SH, Lee JR, Jee BC, Lee BI, Suh CS, et al. Impact of laparoscopic cystectomy on ovarian reserve: serial changes of serum anti-Müllerian hormone levels. Fertil Steril 2010; 94: 343-349. [DOI:10.1016/j.fertnstert.2009.02.022]
8. Chapron C, Dubuisson JB, Fritel X, Rambaud D. Diagnosis and management of organic ovarian cysts: indications and procedures for laparoscopy. Hum Reprod Update 1996; 2: 435-446. [DOI:10.1093/humupd/2.5.435]
9. Konno R, Nagase S, Sato S, Fukaya T, Yajima A. Indications for laparoscopic surgery of ovarian tumors. Tohoku J Exp Med 1996; 178: 225- 231. [DOI:10.1620/tjem.178.225]
10. Suksompong S, Dejarkom S, Petyim S, Dangrat C, Orachon D, Choavaratana R. Ovarian reserve evaluation by anti-mullerian hormone in women undergoing laparoscopic cystectomy of endometrioma. J Med Assoc Thai 2012; 95: 1389-1395.
11. Litta P, D'Agostino G, Conte L, Saccardi C, Cela V, Angioni S, et al. Anti-mullerian hormone trend after laparoscopic surgery in women with ovarian endometrioma. Gynecol Endocrinol 2013; 29: 452-454. [DOI:10.3109/09513590.2012.758704]
12. Sugita A, Iwase A, Goto M, Nakahara T, Nakamura T, Kondo M, et al. One-year follow-up of serum antimüllerian hormone levels in patients with cystectomy: are different sequential changes due to different mechanisms causing damage to the ovarian reserve? Fertil Steril 2013; 100: 516-522. [DOI:10.1016/j.fertnstert.2013.03.032]
13. Alborzi S, Keramati P, Younesi M, Samsami A, Dadras N. The impact of laparoscopic cystectomy on ovarian reserve in patients with unilateral and bilateral endometriomas. Fertil Steril 2014; 101: 427-434. [DOI:10.1016/j.fertnstert.2013.10.019]
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