Volume 13, Issue 4 (5-2015)                   IJRM 2015, 13(4): 237-242 | Back to browse issues page

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Faramarzi A, Khalili M A, Soleimani M. First successful pregnancies following embryo selection using Time-lapse technology in Iran: Case report. IJRM 2015; 13 (4) :237-242
URL: http://ijrm.ir/article-1-639-en.html
First successful pregnancies following embryo selection using Time-lapse technology in Iran: Case report
Azita Faramarzi1 , Mohammad Ali Khalili * 2, Mehrdad Soleimani1
1- Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2- Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , khalili59@hotmail.com
Abstract:   (3884 Views)
Background: Embryo selection is a vital part of in vitro fertilization (IVF) programs, with morphology-based grading systems having been widely used for decades. Time-lapse imaging combined with embryo morph kinetics may proffer a non-invasive means for improving embryo selection. We report the first ongoing and chemical pregnancies using Time-lapse embryo scope to select best embryos for transfer in Iran.
Cases: A case with tubal factor infertility was admitted to IVF program with normozoospermia. After ovarian hyper stimulation, 6 COCs were retrieved and inseminated with 25,000 progressive sperms/ oocyte. Five zygotes were placed individually into the micro wells of equilibrated embryo scope dish for Time-lapse observation, and incubated at 37°C, 5% CO2. On day 3, single embryo transfer (SET) took place based on kinetic parameters of the embryos. Clinical pregnancy was confirmed 7 weeks after SET. The second case with history of previous ICSI failure was admitted with azoospermia. Nine MII oocytes underwent ICSI, and incubated in Time-lapse facilities. The rest of procedures were followed as described for case 1. Chemical pregnancy was confirmed 15 days after SET.
Conclusion: This approach opens a way to select best embryo non-invasively for SET; thus, increasing implantation, while reducing multiple pregnancy complications.
Keywords: Kinetics, Time-lapse, Embryo, Selection.
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Type of Study: Original Article |
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