Volume 14, Issue 10 (10-2016)                   IJRM 2016, 14(10): 665-668 | Back to browse issues page

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Rajaei S, Akbari Sene A, Norouzi S, Berangi Y, Arabian S, Lak P et al . The relationship between serum vitamin D level and premenstrual syndrome in Iranian women. IJRM 2016; 14 (10) :665-668
URL: http://ijrm.ir/article-1-694-en.html
The relationship between serum vitamin D level and premenstrual syndrome in Iranian women
Samira Rajaei1 , Azadeh Akbari Sene * 2, Sara Norouzi3 , Yasrin Berangi3 , Sahereh Arabian3 , Parvaneh Lak3 , Ali Dabbagh4
1- School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
2- Department of Obstetrics and Gynecology, Shahid Akbar-abadi Hospital IVF Center, Iran University of Medical Sciences, Tehran, Iran , doctor_asturias@yahoo.com
3- Department of Obstetrics and Gynecology, Shahid Akbar-abadi Hospital IVF Center, Iran University of Medical Sciences, Tehran, Iran
4- Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:   (3899 Views)
Background: Premenstrual syndrome (PMS) is among the most unfavorable problems in women in reproductive age; however its pathophysiology is still not fully confirmed. Vitamin D as an immunomodulator could prevent inflammatory state before and during menstruation.
Objective: The aim was to investigate whether there is any relationship between serum vitamin D levels and PMS.
Materials and Methods: In total, 82 women participate in this case-control study which was conducted in Shahid Akbar-abadi hospital from November 2013 to March 2015. Categorization was based on an Iranian version of the premenstrual symptoms screening tool (PSST). Levels of 25 hydroxy-vitamin D3 (25OHD) were determined by using 25-OH Vitamin D ELISA kit in luteal phase. Characteristics of participants and vitamin D levels were compared between two groups by using independent sample t-test.
Results: Menarche age of women with PMS was significantly lower than normal women (p=0.04). Body mass index was not statistically different between groups. We observed a high rate of vitamin D deficiency and also its severe deficiency in both PMS and non-PMS groups. However, our study demonstrated no significant difference in the levels of serum 25OHD between the two groups.
Conclusion: It seems there is no association between PMS and serum levels of vitamin D3; however, the high rate of vitamin D deficiency amon
Keywords: Vitamin D, Premenstrual syndrome, Body mass index, Menarche, Premenstrual dysphonic disorder.
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Type of Study: Original Article |
References
1. Rapkin AJ, Akopians AL. Pathophysiology of premenstrual syndrome and premenstrual dysphoric disorder. Menopause Int 2012; 18: 52-59. [DOI:10.1258/mi.2012.012014]
2. Bertone-Johnson ER, Chocano-Bedoya PO, Zagarins SE, Micka AE, Ronnenberg AG. Dietary vitamin D intake, 25-hydroxyvitamin D3 levels and premenstrual syndrome in a college-aged population. J Steroid Biochem Mol Biol 2010; 121: 434-437. [DOI:10.1016/j.jsbmb.2010.03.076]
3. Bertone-Johnson ER, Hankinson SE, Bendich A, Johnson SR, Willett WC, Manson JE. Calcium and vitamin D intake and risk of incident premenstrual syndrome. Arch Intern Med 2005; 165: 1246-1252. [DOI:10.1001/archinte.165.11.1246]
4. Bertone-Johnson ER, Ronnenberg AG, Houghton SC, Nobles C, Zagarins SE, Takashima-Uebelhoer BB, et al. Association of inflammation markers with menstrual symptom severity and premenstrual syndrome in young women. Hum Reprod 2014; 29: 1987-1994. [DOI:10.1093/humrep/deu170]
5. Braverman PK. Premenstrual Syndrome and Premenstrual Dysphoric Disorder. J Pediatr Adolesc Gynecol 2007; 20: 3-12. [DOI:10.1016/j.jpag.2006.10.007]
6. Hariri FZ, Moghaddam-Banaem L, Siah Bazi S, Saki Malehi A, Montazeri A. The Iranian version of the Premenstrual Symptoms Screening Tool (PSST): a validation study. Arch Womens Ment Health 2013;16: 531-537. [DOI:10.1007/s00737-013-0375-6]
7. Thys-Jacobs S, McMahon D, Bilezikian JP. Cyclical changes in calcium metabolism across the menstrual cycle in women with premenstrual dysphoric disorder. J Clin Endocrinol Metab 2007; 92: 2952-2959. [DOI:10.1210/jc.2006-2726]
8. Karapanou O, Papadimitriou A. Determinants of menarche. Reprod Biol Endocrinol 2010; 8: 115. [DOI:10.1186/1477-7827-8-115]
9. Boonchaya-anant P, Holick MF, Apovian CM. Serum 25-hydroxyvitamin D levels and metabolic health status in extremely obese individuals. Obesity (Silver Spring) 2014; 22: 2539-2543. [DOI:10.1002/oby.20877]
10. Jari M, Qorbani M, Moafi M, Motlagh ME, Keikha M, Ardalan G, et al. Association of 25-hydroxy Vitamin D levels with indexes of general and abdominal obesity in Iranian adolescents: The CASPIAN-III study. J Res Med Sci 2015; 20: 122-126.
11. Obeidat BA, Alchalabi HA, Abdul-Razzak KK, Al-Farras MI. Premenstrual symptoms in dysmenorrheic college students: prevalence and relation to vitamin D and parathyroid hormone levels. Int J Environ Res Public Health 2012; 9: 4210-4222. [DOI:10.3390/ijerph9114210]
12. Bertone-Johnson ER, Hankinson SE, Forger NG, Powers SI, Willett WC, Johnson SR, et al. Plasma 25-hydroxyvitamin D and risk of premenstrual syndrome in a prospective cohort study. BMC Womens Health 2014; 14: 56. [DOI:10.1186/1472-6874-14-56]
13. Faghih S, Abdolahzadeh M, Mohammadi M, Hasanzadeh J. Prevalence of vitamin d deficiency and its related factors among university students in shiraz, iran. Int J Prev Med 2014; 5: 796-799.
14. Kaykhaei MA, Hashemi M, Narouie B, Shikhzadeh A, Rashidi H, Moulaei N, et al. High prevalence of vitamin D deficiency in Zahedan, southeast Iran. Ann Nutr Metab 2011; 58: 37-41. [DOI:10.1159/000323749]
15. Hovsepian S, Amini M, Aminorroaya A, Amini P, Iraj B. Prevalence of vitamin D deficiency among adult population of Isfahan City, Iran. J Health Popul Nutr 2011; 29: 149-155. [DOI:10.3329/jhpn.v29i2.7857]
16. Heshmat R, Mohammad K, Majdzadeh SR, Forouzanfar MH, Bahrami A, Ranjbar Omrani GH, et al. Vitamin D Deficiency in Iran: A Multi-center Study among Different Urban Areas. Iran J Public Health 2008; 37 (Suppl.): 72-78.
17. El-Rassi R, Baliki G, Fulheihan GEH. Vitamin D status in Middle East and Africa. Available at: www. iofbonehealth.org/download/osteofound/filemanager/health_professionals/pdf/Vitamin-D-reports/ Vitamin _D-MEast_Africa.pdf Accessed: Jan 2012.
18. Moradzadeh K, Larijani B, Keshtkar AA, Hossein-Nezhad A, Rajabian R, Nabipour I, et al. Normative Values of Vitamin D Among Iranian Population: A Population Based Study. Int J Osteop Metab Disord 2008; 1: 8-15. [DOI:10.3923/ijom.2008.8.15]
19. Hewison M. Vitamin D and immune function: an overview. Proc Nutr Soc 2012; 71: 50-61. [DOI:10.1017/S0029665111001650]
20. Alipour S, Saberi A, Seifollahi A, Shirzad N, Hosseini L. Risk factors and prevalence of vitamin d deficiency among Iranian women attending two university hospitals. Iran Red Crescent Med J 2014; 16: e15461. [DOI:10.5812/ircmj.15461]
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