Volume 14, Issue 3 (3-2016)                   IJRM 2016, 14(3): 181-186 | Back to browse issues page

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Farhadifar F, Khodabandehloo M, Ramazanzadeh R, Rouhi S, Ahmadi A, Ghaderi E, et al . Survey on association between Mycoplasma hominis endocervical infection and spontaneous abortion using Polymerase Chain Reaction. IJRM 2016; 14 (3) :181-186
URL: http://ijrm.ir/article-1-734-en.html
Survey on association between Mycoplasma hominis endocervical infection and spontaneous abortion using Polymerase Chain Reaction
Fariba Farhadifar1 , Mazaher Khodabandehloo2 , Rashid Ramazanzadeh2 , Samaneh Rouhi2 , Amjad Ahmadi * 3, Ebrahim Ghaderi1 , Daem Roshani1 , Nasrin Soofizadeh4 , Masoomeh Rezzaii4
1- Social Determinants of Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran
2- Cellular and Molecular Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran
3- Cellular and Molecular Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran , microbiol_sci@yahoo.com
4- Department of Genecology, Kurdistan University of Medical Sciences, Sanandaj, Iran
Abstract:   (3229 Views)
Background: Mycoplasma infections are suggested as etiology of adverse pregnancy outcomes.
Objective: The aim of this study was to evaluate the association of Mycoplasma hominis (M. hominis) infection and spontaneous abortion among pregnant women.
Materials and Methods: In this case-control study that was conducted from August 2012 to January 2013, totally, 109 women were included with spontaneous abortion with gestational ages of 10-20 weeks (Cases), and 109 women with normal pregnancy with gestational ages between 20-37 weeks (Controls) in Sanandaj, Iran. Using specific primers and extracted DNA from endocervical swabs, a PCR test was conducted for detection of M. hominis infection in women. For comparison of qualitative and quantitative variables, independent Fisher tests were used and          p<0.05 was considered significant.
Results: The total frequency of M. hominis infection was 6 (2.75%) in women. The frequency of M. hominis infection was 2 (1.83%) in the case group (spontaneous abortion) and 4 (3.66%) in the control group, respectively. In both case and control groups, no association was seen between M.hominis infection and spontaneous abortion (OR=0. 49, CI 95%: 0.08-2.73, p=0. 683).
Conclusion: M. hominis was positive in the genital tract of some pregnant women, but it was not associated with spontaneous abortion. However, to prevent adverse pregnancy outcomes in women, foetus and neonate, routine screening and treatment for the genital Mycoplasma is recommended.
Keywords: Mycoplasma hominis, Spontaneous Abortion, Miscarriage, Women
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Type of Study: Original Article |
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