Volume 15, Issue 5 (6-2017)                   IJRM 2017, 15(5): 257-264 | Back to browse issues page

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Faramarzi A, Khalili M A, Micara G, Agha- Rahimi A. Revealing the secret life of pre-implantation embryos by time-lapse monitoring: A review. IJRM 2017; 15 (5) :257-264
URL: http://ijrm.ir/article-1-827-en.html
Revealing the secret life of pre-implantation embryos by time-lapse monitoring: A review
Azita Faramarzi1 , Mohammad Ali Khalili * 2, Giulietta Micara3 , Azam Agha- Rahimi1
1- Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2- Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , khalili59@hotmail.com
3- Department of Obstetrics and Gynecology, UOC OGC03 Infertility and IVF University of Rome La Sapienza, Viale Regina Elena 324-00161 Rome
Abstract:   (3125 Views)
High implantation success following in vitro fertilization cycles are achieved via thetransfer of embryos with the highest developmental competence. Multiplepregnancies as a result of the transfer of several embryos per cycle accompany withvarious complication. Thus, single-embryo transfer (SET) is the preferred practice inassisted reproductive technique (ART) treatment. In order to improve the pregnancyrate for SET, embryologists need reliable biomarkers to aid their selection ofembryos with the highest developmental potential. Time-lapse technology is anoninvasive alternative conventional microscopic assessment. It providesuninterrupted and continues the survey of embryo development to transfer day.Today, there are four time-lapse systems that are commercially available for ARTcenters. In world and Iran, the first time lapse babies were born in 2010 and 2015,respectively, conceived by SET. Here, we review the use of time-lapse monitoring inthe observation of embryogenesis as well as its role in SET. Although, the findingsfrom our review support common use of time-lapse monitoring in ART centers; but,future large studies assessing this system in well-designed trials are necessary
Keywords: Embryo selection, Kinetic, Assisted reproductive technology, Time-lapse.
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Type of Study: Original Article |
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