شنبه 8 دی 1403
[Archive]
دوره 5، شماره 5 - ( 4-1386 )
جلد 5 شماره 5 صفحات 198-195 |
برگشت به فهرست نسخه ها
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Owj M, Mohseni M, Amirchaghmaghi E, Sadeghi M, Eshrati B, Shabani F. The relationship between passive smoking and ovarian response outcome in ART cycles. IJRM 2007; 5 (5) :195-198
URL: http://ijrm.ir/article-1-87-fa.html
URL: http://ijrm.ir/article-1-87-fa.html
The relationship between passive smoking and ovarian response outcome in ART cycles. International Journal of Reproductive BioMedicine. 1386; 5 (5) :195-198
چکیده: (3116 مشاهده)
Background: Smoking has negative effects on reproductive process. Exposing to cigarette smoking (passive smoking) may exert some effects as the direct smoking.
Objective: The aim of this study was to evaluate the correlation between ovarian response and passive smoking in women who underwent ART cycles.
Materials and Methods: One hundred-sixty patients who underwent ICSI between 2000 and 2001 were studied in a prospective cohort study. The case group included women whose husbands smoked at least 5 cigarettes daily for 1 year or more. The control group included women with nonsmoking husbands. Women with high FSH level (>12 IU/ml) were excluded. Long standard protocol with GnRH agonist and HMG were used in all patients. In vitro fertilization and embryo transfer was carried out in a standard fashion.
Results: Eighty one women were in case group and 82 in control group. Ovarian response variables were not significantly different between two groups but there was a significant relation between passive smoking and fertilization (RR= 1.18, 95% CI: 1.07-1.31). However pregnancy rate was not significantly different between two groups. Moreover there were no significant differences between heavy and light smokers in ovarian response outcomes.
Conclusion: This study showed no correlation between ovarian response parameters and passive smoking in women underwent ART cycles, whereas fertilization rate is significantly lower in this group compared to control group. It may be related to sperm quality than oocytes. Assessment of nicotin in follicular fluid and cytogenetic evaluation of embryo before transfer are recommended for more information and confirmation.
Objective: The aim of this study was to evaluate the correlation between ovarian response and passive smoking in women who underwent ART cycles.
Materials and Methods: One hundred-sixty patients who underwent ICSI between 2000 and 2001 were studied in a prospective cohort study. The case group included women whose husbands smoked at least 5 cigarettes daily for 1 year or more. The control group included women with nonsmoking husbands. Women with high FSH level (>12 IU/ml) were excluded. Long standard protocol with GnRH agonist and HMG were used in all patients. In vitro fertilization and embryo transfer was carried out in a standard fashion.
Results: Eighty one women were in case group and 82 in control group. Ovarian response variables were not significantly different between two groups but there was a significant relation between passive smoking and fertilization (RR= 1.18, 95% CI: 1.07-1.31). However pregnancy rate was not significantly different between two groups. Moreover there were no significant differences between heavy and light smokers in ovarian response outcomes.
Conclusion: This study showed no correlation between ovarian response parameters and passive smoking in women underwent ART cycles, whereas fertilization rate is significantly lower in this group compared to control group. It may be related to sperm quality than oocytes. Assessment of nicotin in follicular fluid and cytogenetic evaluation of embryo before transfer are recommended for more information and confirmation.
نوع مطالعه: Original Article |
فهرست منابع
1. Joesbury KA, Edirisinghe WR, Phillips MR, Yovich JL. Evidence that male smoking affects the likelihood of a pregnancy following IVF treatment: application of the modified, cumulative embryo score. Hum Reprod 1998; 13:1506-1513. [DOI:10.1093/humrep/13.6.1506]
2. Gerhard I, Runnebaum B. Environmental contamination and infertility. In: Runnebaum B, Rabe T. Gynecological Endocrinology and Reproductive Medicine,Germany, Springer ,1997; 2:189-191. [DOI:10.1007/978-3-642-60390-7]
3. Ludwig M, Finas DF, al-Hasani S, Diedrich K, Ortmann O. Oocyte quality and treatment outcome in intracytoplasmic sperm injection cycles of polycystic ovarian syndrome patients. Hum Reprod 1999; 14:354-358. [DOI:10.1093/humrep/14.2.354]
4. Scott LA. Analysis of fertilization. In: Gardner D.K, Weissman A, Howles CM, Shoham Z. Textbook of Assisted Reproductive Techniques: Laboratory and clinical perspectives, UK, Taylor & Francis, 2nd Edition 2004:203-205.
5. Sharara FI, Beatse SN, Leonardi MR, Navot D, Scott RT Jr. Cigarette smoking accelerates the development of diminished ovarian reserve as evidenced by the clomiphene citrate challenge test. Fertil Steril 1994; 62:257-262. [DOI:10.1016/S0015-0282(16)56875-7]
6. Zenzes MT, Reed TE, Casper RF. Effects of cigarette smoking and age on the maturation of human oocytes. Hum Reprod 1997; 12:1736-1741. [DOI:10.1093/humrep/12.8.1736]
7. Sterzik K, Strehler E, De Santo M, Trumpp N, Abt M, Rosenbusch B. Schneider A.Influence of smoking on fertility in women attending an in vitro fertilization program. Fertil Steril 1996; 65:810-814. [DOI:10.1016/S0015-0282(16)58219-3]
8. Klonoff-Cohen H, Natarajan L, Marrs R, Yee B. Effects of female and male smoking on success rates of IVF and gamete intra-Fallopian transfer. Hum Reprod 2001; 16:1382-1390. [DOI:10.1093/humrep/16.7.1382]
9. Sun JG, Jurisicova A, Casper RF. Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol Reprod 1997; 56:602-607. [DOI:10.1095/biolreprod56.3.602]
| بازنشر اطلاعات | |
 |
این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است. |
