شنبه 8 دی 1403
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دوره 5، شماره 5 - ( 4-1386 )
جلد 5 شماره 5 صفحات 190-187 |
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Gharabaghi P, Abdollahifard S, Gharabaghi M, Nouri M. Comparing the levels of ßHCG, progesterone and estradiol between ectopic pregnancy and normal intrauterine pregnancy. IJRM 2007; 5 (5) :187-190
URL: http://ijrm.ir/article-1-90-fa.html
URL: http://ijrm.ir/article-1-90-fa.html
Comparing the levels of ßHCG, progesterone and estradiol between ectopic pregnancy and normal intrauterine pregnancy. International Journal of Reproductive BioMedicine. 1386; 5 (5) :187-190
چکیده: (3066 مشاهده)
Background: The value of serial measurement of serum ß subunit of human chorionic gonadotropin (ßHCG) and ultrasonography in the early diagnosis of ectopic pregnancy has well established.
Objective: The objective of this study was to explore the diagnostic value of raising level of serum ßHCG, single measurement of progesterone (P) and estradiol (E2) in early diagnosis of ectopic pregnancy.
Materials and Methods: Serum levels of ßHCG and estradiol were measured by Radio Immuno Sorbent Assay (RIA) and progesterone level was measured by Enzyme Linked Immuno Sorbent Assay (ELISA) techniques in 43 symptomatic women with ectopic pregnancy and 42 women with normal intrauterine pregnancy in Alzahra Hospital, Tabriz, Iran. These values were compared by T-test. By determining cut-off levels of these parameters the efficiency and sensitivity of them in prediction of ectopic pregnancy was estimated.
Results: The mean serum levels of ßHCG, estradiol and progesterone in patients with ectopic pregnancies (940 ± 552 mlu/ml, 593 ± 237 pg/ml, 5.83 ± 3.41 ng/ml, respectively) were significantly lower than these levels in normal intrauterine pregnancies (4620 ± 2030 mlu/ml, 1627 ± 435 pg/ml, 24.8 ± 6.08 ng/ml, respectively). The average rate of ßHCG rising was 8.2% for 24 hours in patients with ectopic pregnancy (EP) and 32.8% in normal intrauterine pregnancies (NIUP).
Conclusions: In this study single measurement of serum progesterone level has the greatest sensitivity (100%) and specificity (98%) in the diagnosis of ectopic pregnancy.
Objective: The objective of this study was to explore the diagnostic value of raising level of serum ßHCG, single measurement of progesterone (P) and estradiol (E2) in early diagnosis of ectopic pregnancy.
Materials and Methods: Serum levels of ßHCG and estradiol were measured by Radio Immuno Sorbent Assay (RIA) and progesterone level was measured by Enzyme Linked Immuno Sorbent Assay (ELISA) techniques in 43 symptomatic women with ectopic pregnancy and 42 women with normal intrauterine pregnancy in Alzahra Hospital, Tabriz, Iran. These values were compared by T-test. By determining cut-off levels of these parameters the efficiency and sensitivity of them in prediction of ectopic pregnancy was estimated.
Results: The mean serum levels of ßHCG, estradiol and progesterone in patients with ectopic pregnancies (940 ± 552 mlu/ml, 593 ± 237 pg/ml, 5.83 ± 3.41 ng/ml, respectively) were significantly lower than these levels in normal intrauterine pregnancies (4620 ± 2030 mlu/ml, 1627 ± 435 pg/ml, 24.8 ± 6.08 ng/ml, respectively). The average rate of ßHCG rising was 8.2% for 24 hours in patients with ectopic pregnancy (EP) and 32.8% in normal intrauterine pregnancies (NIUP).
Conclusions: In this study single measurement of serum progesterone level has the greatest sensitivity (100%) and specificity (98%) in the diagnosis of ectopic pregnancy.
نوع مطالعه: Original Article |
فهرست منابع
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