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Volume 15, Issue 12 (12-2017)
IJRM 2017, 15(12): 803-806 |
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Farimani M, Poorolajal J, Rabiee S, Bahmanzadeh M. Successful pregnancy and live birth after intrauterine administration of autologous platelet-rich plasma in a woman with recurrent implantation failure: A case report. IJRM 2017; 15 (12) :803-806
URL: http://ijrm.ir/article-1-931-en.html
URL: http://ijrm.ir/article-1-931-en.html
1- Endometrium and Endometriosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
2- Research Center for Health Sciences, Hamadan University of Medical sciences, Hamadan, Iran
3- Endometrium and Endometriosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran , Bahmanzadeh12@yahoo.com
2- Research Center for Health Sciences, Hamadan University of Medical sciences, Hamadan, Iran
3- Endometrium and Endometriosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran , Bahmanzadeh12@yahoo.com
Abstract: (3176 Views)
Background: Platelets contain a significant amount of growth factors that have positive effects on local tissue repair and endometrial receptivity.
Case: Here we present a 45-yr-old woman with primary infertility and two failed in vitro fertilization (IVF) cycles who was candidate to receive donor eggs. Five consecutive frozen-thawed embryo transfer cycles with good quality embryos were performed within 2 yr. With the diagnosis of recurrent implantation failure (RIF), the patient was treated for improving endometrial receptivity with intrauterine administration of autologous platelet-rich plasma (PRP), 24 hr before embryo transfer. The patient gave birth to a healthy baby boy weighing 2350 gr in the cesarean section.
Conclusion: Extensive literature search suggests that this is the first successful pregnancy after administration of PRP in a woman with RIF. Local administration of PRP before embryo transfer may play a vital role in successful implantation
Case: Here we present a 45-yr-old woman with primary infertility and two failed in vitro fertilization (IVF) cycles who was candidate to receive donor eggs. Five consecutive frozen-thawed embryo transfer cycles with good quality embryos were performed within 2 yr. With the diagnosis of recurrent implantation failure (RIF), the patient was treated for improving endometrial receptivity with intrauterine administration of autologous platelet-rich plasma (PRP), 24 hr before embryo transfer. The patient gave birth to a healthy baby boy weighing 2350 gr in the cesarean section.
Conclusion: Extensive literature search suggests that this is the first successful pregnancy after administration of PRP in a woman with RIF. Local administration of PRP before embryo transfer may play a vital role in successful implantation
Keywords: Recurrent implantation failure, Platelet-rich plasma, Embryo transfer, Assisted reproductive technology, Pregnancy outcome, Embryo implantation
Type of Study: Original Article |
References
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