Volume 14, Issue 10 (10-2016)                   IJRM 2016, 14(10): 665-668 | Back to browse issues page

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Rajaei S, Akbari Sene A, Norouzi S, Berangi Y, Arabian S, Lak P et al . The relationship between serum vitamin D level and premenstrual syndrome in Iranian women. IJRM 2016; 14 (10) :665-668
URL: http://ijrm.ir/article-1-694-en.html
The relationship between serum vitamin D level and premenstrual syndrome in Iranian women
Samira Rajaei1 , Azadeh Akbari Sene * 2, Sara Norouzi3 , Yasrin Berangi3 , Sahereh Arabian3 , Parvaneh Lak3 , Ali Dabbagh4
1- School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
2- Department of Obstetrics and Gynecology, Shahid Akbar-abadi Hospital IVF Center, Iran University of Medical Sciences, Tehran, Iran , doctor_asturias@yahoo.com
3- Department of Obstetrics and Gynecology, Shahid Akbar-abadi Hospital IVF Center, Iran University of Medical Sciences, Tehran, Iran
4- Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:   (3900 Views)
Background: Premenstrual syndrome (PMS) is among the most unfavorable problems in women in reproductive age; however its pathophysiology is still not fully confirmed. Vitamin D as an immunomodulator could prevent inflammatory state before and during menstruation.
Objective: The aim was to investigate whether there is any relationship between serum vitamin D levels and PMS.
Materials and Methods: In total, 82 women participate in this case-control study which was conducted in Shahid Akbar-abadi hospital from November 2013 to March 2015. Categorization was based on an Iranian version of the premenstrual symptoms screening tool (PSST). Levels of 25 hydroxy-vitamin D3 (25OHD) were determined by using 25-OH Vitamin D ELISA kit in luteal phase. Characteristics of participants and vitamin D levels were compared between two groups by using independent sample t-test.
Results: Menarche age of women with PMS was significantly lower than normal women (p=0.04). Body mass index was not statistically different between groups. We observed a high rate of vitamin D deficiency and also its severe deficiency in both PMS and non-PMS groups. However, our study demonstrated no significant difference in the levels of serum 25OHD between the two groups.
Conclusion: It seems there is no association between PMS and serum levels of vitamin D3; however, the high rate of vitamin D deficiency amon
Keywords: Vitamin D, Premenstrual syndrome, Body mass index, Menarche, Premenstrual dysphonic disorder.
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Type of Study: Original Article |
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