Volume 15, Issue 1 (1-2017)                   IJRM 2017, 15(1): 17-20 | Back to browse issues page


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Sattari M, Ghiami Rad M, Ghasemzadeh A, Mohammadoghli Reihan Z. Frequency of anti-Chlamydia trachomatis antibodies in infertile women referred to Al-Zahra hospital in Tabriz. IJRM. 2017; 15 (1) :17-20
URL: http://ijrm.ssu.ac.ir/article-1-792-en.html
1- Microbiology Department, Faculty of Basic Sciences, Islamic Azad University, Ahar Branch, Ahar, Iran.
2- Microbiology Department, Faculty of Basic Sciences, Islamic Azad University, Ahar Branch, Ahar, Iran. , M_ghiyamirad@yahoo.com; m-ghiamirad@Iau-ahar.ac
3- Department of Obstetrics and Gynecology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract:   (2120 Views)
Background: Infertility is one of the major issues in society and its incidence is estimated to be almost 10-15%.. Chlamydia is an important cause of sexually transmitted diseases leading to infertility.
Objective: This study was designed to determine the frequency of anti-Chlamydia trachomatis (anti-C. trachomatis) antibodies in infertile women at Alzahra hospital, Tabriz, Iran.
Materials and Methods: In this cross-sectional study, the blood samples were collected randomly from 184 infertile women (case group) and 100 pregnant women (control group).the frequency of specific IgG and IgM anti-Chlamydia trachomatis antibodies were evaluated using ELISA.
Results: The frequency of anti-C. trachomatis IgG in pregnant and infertile women was 18% and 35.88%, respectively. The frequency of anti- C. trachomatis IgM in pregnant and infertile women was 2% and 5.44%.Our results showed the significant high rate of anti-Chlamydia trachomatis IgG (p=0.035), IgM (p=0.004) (p<0.05) in infertile women. Also, no significant relation was seen in the frequency of antibody between urban and rural women, IgG (p=0.690), IgM (p=0.486). The highest prevalence of positive cases was seen among the 21-30 years of age groups. There was not a significant relationship between age of infertile women and the amount of anti-Chlamydia trachomatis antibody, IgG (p=0.437), IgM (p=0.132). There was no significant relationship between tubal factor infertility and the frequency of anti C. trachomatis antibodies, IgG (p=0.208), IgM (p=0.082) (p>0.05).
Conclusion: According to the high frequency of antibody anti-C. trachomatis among infertile women in competition to the control group, evaluation and treatment of Chlamydia infections is necessary in these patients.
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