International Journal of
Reproductive Biomedicine
Sun, Dec 22, 2024
[Archive]
Volume 15, Issue 1 (1-2017)
IJRM 2017, 15(1): 17-20 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Sattari M, Ghiami Rad M, Ghasemzadeh A, Mohammadoghli Reihan Z. Frequency of anti-Chlamydia trachomatis antibodies in infertile women referred to Al-Zahra hospital in Tabriz. IJRM 2017; 15 (1) :17-20
URL: http://ijrm.ir/article-1-792-en.html
URL: http://ijrm.ir/article-1-792-en.html
1- Microbiology Department, Faculty of Basic Sciences, Islamic Azad University, Ahar Branch, Ahar, Iran.
2- Microbiology Department, Faculty of Basic Sciences, Islamic Azad University, Ahar Branch, Ahar, Iran. ,M_ghiyamirad@yahoo.com; m-ghiamirad@Iau-ahar.ac
3- Department of Obstetrics and Gynecology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
2- Microbiology Department, Faculty of Basic Sciences, Islamic Azad University, Ahar Branch, Ahar, Iran. ,
3- Department of Obstetrics and Gynecology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract: (3134 Views)
Background: Infertility is one of the major issues in society and its incidence is estimated to be almost 10-15%.. Chlamydia is an important cause of sexually transmitted diseases leading to infertility.
Objective: This study was designed to determine the frequency of anti-Chlamydia trachomatis (anti-C. trachomatis) antibodies in infertile women at Alzahra hospital, Tabriz, Iran.
Materials and Methods: In this cross-sectional study, the blood samples were collected randomly from 184 infertile women (case group) and 100 pregnant women (control group).the frequency of specific IgG and IgM anti-Chlamydia trachomatis antibodies were evaluated using ELISA.
Results: The frequency of anti-C. trachomatis IgG in pregnant and infertile women was 18% and 35.88%, respectively. The frequency of anti- C. trachomatis IgM in pregnant and infertile women was 2% and 5.44%.Our results showed the significant high rate of anti-Chlamydia trachomatis IgG (p=0.035), IgM (p=0.004) (p<0.05) in infertile women. Also, no significant relation was seen in the frequency of antibody between urban and rural women, IgG (p=0.690), IgM (p=0.486). The highest prevalence of positive cases was seen among the 21-30 years of age groups. There was not a significant relationship between age of infertile women and the amount of anti-Chlamydia trachomatis antibody, IgG (p=0.437), IgM (p=0.132). There was no significant relationship between tubal factor infertility and the frequency of anti C. trachomatis antibodies, IgG (p=0.208), IgM (p=0.082) (p>0.05).
Conclusion: According to the high frequency of antibody anti-C. trachomatis among infertile women in competition to the control group, evaluation and treatment of Chlamydia infections is necessary in these patients.
Objective: This study was designed to determine the frequency of anti-Chlamydia trachomatis (anti-C. trachomatis) antibodies in infertile women at Alzahra hospital, Tabriz, Iran.
Materials and Methods: In this cross-sectional study, the blood samples were collected randomly from 184 infertile women (case group) and 100 pregnant women (control group).the frequency of specific IgG and IgM anti-Chlamydia trachomatis antibodies were evaluated using ELISA.
Results: The frequency of anti-C. trachomatis IgG in pregnant and infertile women was 18% and 35.88%, respectively. The frequency of anti- C. trachomatis IgM in pregnant and infertile women was 2% and 5.44%.Our results showed the significant high rate of anti-Chlamydia trachomatis IgG (p=0.035), IgM (p=0.004) (p<0.05) in infertile women. Also, no significant relation was seen in the frequency of antibody between urban and rural women, IgG (p=0.690), IgM (p=0.486). The highest prevalence of positive cases was seen among the 21-30 years of age groups. There was not a significant relationship between age of infertile women and the amount of anti-Chlamydia trachomatis antibody, IgG (p=0.437), IgM (p=0.132). There was no significant relationship between tubal factor infertility and the frequency of anti C. trachomatis antibodies, IgG (p=0.208), IgM (p=0.082) (p>0.05).
Conclusion: According to the high frequency of antibody anti-C. trachomatis among infertile women in competition to the control group, evaluation and treatment of Chlamydia infections is necessary in these patients.
Type of Study: Original Article |
References
1. Tabong P, Adongo PB. Understanding the Social Meaning of the Infertility and Childbearing: A Qualitative Study of the Perception of Childbearingand and Childlessness in Northern Ghana. PLOS ONE 2013; 8: e54429. [DOI:10.1371/journal.pone.0054429]
2. Bayley TM, Slade P, Lashen H. Relationships between attachment, appraisal, coping and adjustment in men and women experiencing infertility concerns. Hum Reprod 2009; 24: 2827-2837. [DOI:10.1093/humrep/dep235]
3. Faria DEP, Grieco SC, Barros SMO. The effects of infertility on the spouses' relationship. Rev Esc Enferm USP 2012; 46: 794-801. [DOI:10.1590/S0080-62342012000400002]
4. Speroff L, Fritz MA. Clinical gynecologic
5. Maheshwari A, Hamilton M, Bhattacharay S. Effect of female age on the diagnostic categorise of infertility. Hum Reprod 2008; 23: 538-542. [DOI:10.1093/humrep/dem431]
6. Akbari S, Vahabi S, Kazwmi AH. [Knowledge of working women in Hospitals of Lorestan Medical Sciences University about smoking effects on fertility]. J Reprod Infertil 2002; 3: 59-64. (In Persian)
7. Ryan KJ, Berkowitz RS, Barbieri RL, Dunaif A. The infertile couple, MitchellS. In: Kistner's gynecology and women's Health, 7PthP Ed. Mosby 1999: 340.
8. Brek JS. Novak's gynecology. 14PthP Ed. London: Lippincott; 2007; 1088-1165.
9. Joyee AG, Thyagarajan SP, Reddy EV, Venkatesanc C, Ganapathy M. Genital Chlamydia infection in STD patients: its relation on HIV infection. Indian J Med Microbiol 2005; 23: 37-40. [DOI:10.4103/0255-0857.13871]
10. Adams EJ, Charlett A, Edmunds WJ, Hughes G. Chlamydia trachomatis in the United Kingdom: a systematic review and analysis of prevalence studies. J Sex Transm Infect 2004; 80: 354-362. [DOI:10.1136/sti.2003.005454]
11. 66TJosefson66T D. Chlamydia increases risk of Cervial cancer. BMJ 2001; 322: 71. [DOI:10.1136/bmj.322.7278.71]
12. Chamani L. [Chlamydia and fertility]. J Fertil Infertil 2000; 2: 68-74. (In Persian)
13. Gerbase AC, Rewley JT, Mertens TE. Global [DOI:10.1016/S0140-6736(98)90001-0]
14. Lee YS, Lee KS. Chlamydia and Male lower urinary tract diseases. Koream J Urol 2013; 54: 73-77. [DOI:10.4111/kju.2013.54.2.73]
15. Dixon RE, Hwang SJ, Hennig GW, Ramsey HK, Schripsema HJ, Sanders KM, Ward SM. Chlamydia infection causes loss of pacemaker cells and inhibits Oocyte transport in the mouse oviduct. Biol Reprod 2009; 80: 665-673. [DOI:10.1095/biolreprod.108.073833]
16. Malik A, Jain S, Hakim S, Shukla I,Rizvi M.Chlamydia trachomatis infection and female infertility. Indian J Med Res 2006; 123: 770-775.
17. Badami N, Salari MH. Rate of Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum in infertile females and control group. Iran J Public Health 2001; 30: 57-60. (In Persian)
18. Nikbakht R, Razi T, Ghalambor Dezfouli F, Saharkhiz N. Comparison of hysterosalpingography and laparoscopy in evaluating tubal and peritoneal factors in infertile patients. Jundishapur Sci Med J 2006; 5: 607-613. (In Persian)
19. Surana A, Rastogi V, Nirwan PS. Association of the serum anti-Chlamydial antibodies with tubal infertility. J Clin Diagn Res 2012; 6: 1692-1694. [DOI:10.7860/JCDR/2012/3771.2632]
20. Fanaei H, Mardaneh J, Khayat S. [A review of the role of bacterial infections in male infertility]. J Fasa Med Sci 2012; 2: 227-234. (In Persian)
21. Sönmez S, Sönmez E, Yasar L, Aydin F, Coskun A, Süt N. Can screening Chlamydia trachomatis by serological tests predict tubal damage in infertile patients? New Microbiol 2008; 31: 75-79.
22. Omo-Aghoja LO, Okonofua FE, Onemu SO, Larsen U, Bergstrom S. Association of Chlamydia trachomatis serology with tubal infertility in Nigerian women. J Obstet Gynaecol Res 2007; 33: 688-695. [DOI:10.1111/j.1447-0756.2007.00633.x]
23. Sotoudeh Jahromi AAR, Safa o, Zare SH. Anti-Chlamydia trachomatis antibodies and abortion in women referting to Shariati hospital of Bandar Abbas. Med J Hormozgan Univ 2005; 8: 185-188. (In Persian)
24. Siemer J, Theile O, Larbi Y, Fasching PA, Danso KA, Kreienberg R, et al. Chlamydia trachomatis infection as a risk factor for infertility among women in Ghana, West Africa. Am J Trop Med Hyg 2008; 78: 323-327.
25. Rashidi B, Chamani Tabriz L, Hagh ol- Allah F, Ramazan Zadeh F, Shareeat M, Rahimi Forooshani A, et al. [Infection with Chlamydia trachomatis in fertile and infertile women with Serological and Molecular method]. J Fertil Infertil 2009; 32-41. (In Persian)
26. Chen XS, Yin YP, Chen LP, Thuy NT, Zhang GY, Shi MQ, et al. Sexually transmitted infections among pregnant women attending an antenatal clinic in Fuzhou, China. Sex Transm Dis 2006; 33: 296-301. [DOI:10.1097/01.olq.0000194580.02116.6b]
27. Basirat Z, Sharbatdaran M, Montazer F. Comparison of anti-Chlamydia antibodies in tubal and non-tubal infertile patients. J Mazandaran Univ Med Sci 2006; 16: 24-118. (In Persian)
28. Sharma M, Sethi S, Daftari S, Malgotra P. Eviderce of chlamydial infection in infertile women with fallopian tube obstruction. Indian J Pathol Microbiol 2003; 46: 680-683.
29. Keltz MD, Sauerbru MT, Durante MS, Moshier E, Stein DE, Gonzales E. Positive Chlamydia trachomatis serology result in women seeking care for infertility is a negative prognostiictor for intrauterine pregnancy. Sex Transm Dis 2013; 40: 842-845. [DOI:10.1097/OLQ.0000000000000035]
30. Idahl A, Boman J, Kumlin U, Olofsson JI. Demonstration of clamydia trachomatis IgG antibodies in the male partner of the infertile is corrected with a reduced likehood of achieving pregnancy. Hum Reprod 2004; 19: 1121-1126 [DOI:10.1093/humrep/deh155]
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
