Volume 20, Issue 11 (November 2022)                   IJRM 2022, 20(11): 963-972 | Back to browse issues page

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Ahmadizad P, Shohani M, Direkvand Moghadam A, Jalilian A, Sayadi H, Abbasi N. Comparison of the effect of licorice vaginal cream and estrogen vaginal cream on sexual function of postmenopausal women: An RCT. IJRM 2022; 20 (11) :963-972
URL: http://ijrm.ir/article-1-2500-en.html
Comparison of the effect of licorice vaginal cream and estrogen vaginal cream on sexual function of postmenopausal women: An RCT
Parisa Ahmadizad1 , Masoumeh Shohani * 2, Ashraf Direkvand Moghadam3 , Anahita Jalilian4 , Hojat Sayadi5 , Naser Abbasi6
1- Department of Nursing, School of Nursing and Midwifery, Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran.
2- Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran. , msh282000@gmail.com
3- Department of Midwifery, School of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran.
4- Department of Obstetrics and Gynecology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
5- Department of Biostatistics, School of Health, Non-Communicable Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran.
6- Department of Pharmacology, School of Medicine, Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Abstract:   (922 Views)
Background: Menopause is a stage in woman’s life that some women experience in middle age and some at a younger age (premature menopause). Low levels of ovarian hormones, during menopause can lead to various complications. Menopause is one of the factors that can affect a woman's sexual function.
Objective: The present study was conducted to compare the effect of licorice vaginal cream and estrogen vaginal cream on the sexual function of postmenopausal women.
Materials and Methods: In this randomized clinical trial study, 82 postmenopausal women who were referred to health centers in Ilam, Iran from July to November 2020 were randomly divided into 2 groups (n = 41/each). One group was given estrogen vaginal cream 2%, and the other vaginal licorice cream 2%. Participants used the 2 medications for 14-day periods each. We used the finite randomization method. Data collection questionnaires, including a demographic information questionnaire before treatment and a female sexual function index questionnaire were completed before, one month after the medication, and 2 months after using the medication.
Results: The mean score of sexual function in the licorice group was 17.86 ± 4.37 and increased to 20.31 ± 4.63 at the end of the study. The mean score of sexual function in the estrogen group was 17.14 ± 3.99 and increased to 22.97 ± 5.09 at the end of study (p = 0.015).
Conclusion: The effect of estrogen vaginal cream on the sexual function of postmenopausal women was greater than licorice vaginal cream.
Keywords: Vagina, Post menopause, Glycyrrhiza, Estrogens.
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Type of Study: Original Article | Subject: Reproductive Epidemiology
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