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Volume 21, Issue 3 (March 2023)
IJRM 2023, 21(3): 205-212 |
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Bahrami F, Eftekhar M, Zanbagh L. Uterine artery Doppler and endometrial blood flow in frozen embryo transfer: A cohort study. IJRM 2023; 21 (3) :205-212
URL: http://ijrm.ir/article-1-2676-en.html
URL: http://ijrm.ir/article-1-2676-en.html
1- Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. ,eftekharmaryam@yahoo.com
3- Department of Obstetrics and Gynecology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. ,
3- Department of Obstetrics and Gynecology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Abstract: (886 Views)
Background: The implantation rate after assisted reproductive technology depends on 2 important factors, good quality embryo and endometrial receptivity. Endometrial receptivity is mainly assessed by ultrasound measurement of endometrial thickness and morphology.
Objective: This study aimed to investigate the relationship between uterine artery Doppler indices/endometrial perfusion and pregnancy rate.
Materials and Methods: This cohort study was done on 250 women who were candidates for frozen embryo transfer from January to July 2022. For assessing endometrial receptivity, we performed a Doppler ultrasound of the uterus before embryo transfer with apparently desirable endometrium (endometrial thickness ≥ 7 mm and 3 line endometrial pattern). In addition, the women were divided into 2 groups according to assisted reproductive technology outcome (clinical pregnancy), group I positive clinical pregnancy, and group II negative clinical pregnancy, and uterine artery indices and endometrial perfusion were compared between these groups.
Results: Uterine artery Doppler showed that the pulsatility index was significantly different between positive and negative clinical pregnancy groups, but resistance index and peak systolic velocity (PSV) did not have statistically significant differences. Also, endometrial perfusion was significantly different between the 2 groups of clinical pregnancy. Endometrial perfusion was significantly better in positive clinical pregnancy groups.
Conclusion: Doppler ultrasound can help to assess endometrial receptivity.
Objective: This study aimed to investigate the relationship between uterine artery Doppler indices/endometrial perfusion and pregnancy rate.
Materials and Methods: This cohort study was done on 250 women who were candidates for frozen embryo transfer from January to July 2022. For assessing endometrial receptivity, we performed a Doppler ultrasound of the uterus before embryo transfer with apparently desirable endometrium (endometrial thickness ≥ 7 mm and 3 line endometrial pattern). In addition, the women were divided into 2 groups according to assisted reproductive technology outcome (clinical pregnancy), group I positive clinical pregnancy, and group II negative clinical pregnancy, and uterine artery indices and endometrial perfusion were compared between these groups.
Results: Uterine artery Doppler showed that the pulsatility index was significantly different between positive and negative clinical pregnancy groups, but resistance index and peak systolic velocity (PSV) did not have statistically significant differences. Also, endometrial perfusion was significantly different between the 2 groups of clinical pregnancy. Endometrial perfusion was significantly better in positive clinical pregnancy groups.
Conclusion: Doppler ultrasound can help to assess endometrial receptivity.
Type of Study: Original Article |
Subject:
Fertility & Infertility
References
1. Kim A, Jung H, Choi WJ, Hong SN, Kim HY. Detection of endometrial and subendometrial vasculature on the day of embryo transfer and prediction of pregnancy during fresh in vitro fertilization cycles. Taiwan J Obstet Gynecol 2014; 53: 360-365. [DOI:10.1016/j.tjog.2013.05.007] [PMID]
2. Zebitay AG, Tutumlu M, Verit FF, Ilhan GK, Gungor ES, Cetin O, et al. A comparative analysis of arterial blood flow in unexplained infertility, tubal infertility and fertile groups. Gynecol Endocrinol 2016; 32: 442-445. [DOI:10.3109/09513590.2015.1126709] [PMID]
3. Crosby DA, Glover LE, Downey P, Mooney EE, McAuliffe FM, O'Farrelly C, et al. Mid-luteal uterine artery Doppler indices in the prediction of pregnancy outcome in nulliparous women undergoing assisted reproduction. Hum Fertil 2022; 25: 670-676. [DOI:10.1080/14647273.2021.1872111] [PMID]
4. Sardana D, Upadhyay AJ, Deepika K, Pranesh GT, Rao KA. Correlation of subendometrial-endometrial blood flow assessment by two-dimensional power Doppler with pregnancy outcome in frozen-thawed embryo transfer cycles. J Hum Reprod Sci 2014; 7: 130-135. [DOI:10.4103/0974-1208.138872] [PMID] [PMCID]
5. El-Mazny A, Abou-Salem N, ElShenoufy H. Doppler study of uterine hemodynamics in women with unexplained infertility. Eur J Obstet Gynecol Reprod Biol 2013; 171: 84-87. [DOI:10.1016/j.ejogrb.2013.08.026] [PMID]
6. Singh N, Bahadur A, Mittal S, Malhotra N, Bhatt A. Predictive value of endometrial thickness, pattern and sub-endometrial blood flows on the day of hCG by 2D doppler in in-vitro fertilization cycles: A prospective clinical study from a tertiary care unit. J Hum Reprod Sci 2011; 4: 29-33. [DOI:10.4103/0974-1208.82357] [PMID] [PMCID]
7. Ali zarad C, Mohamed MH, Shanab WSA. Role of uterine artery Doppler in assessment of unexplained infertility. Egypt J Radiol Nuclear Med 2021; 52: 59. [DOI:10.1186/s43055-021-00430-3]
8. Moramezi F, Barati M, Mosavi Mobarakeh M. A comparative study of uterine artery blood flow in patients with unexplained infertility and normal fertile women using Doppler sonography. Int J Pharm Res Allied Sci 2016; 5: 221-228.
9. Makhija K, Shrivasatava D, Tiwari M. Predictive value of uterine artery: Peak systolic velocity on the day of trigger for clinical pregnancy rate in infertile women. Int J Reprod Contracept Obstet Gynecol 2019; 8: 677-682. [DOI:10.18203/2320-1770.ijrcog20190304]
10. Maged AM, Kamel AM, Abu-Hamila F, Elkomy RO, Ohida OA, Hassan SM, et al. The measurement of endometrial volume and sub-endometrial vascularity to replace the traditional endometrial thickness as predictors of in-vitro fertilization success. Gynecol Endocrinol 2019; 35: 949-954. [DOI:10.1080/09513590.2019.1604660] [PMID]
11. Riad ON, Hak AA. Assessment of endometrial receptivity using Doppler ultrasonography in infertile women undergoing intrauterine insemination. Gynecol Endocrinol 2014; 30: 70-73. [DOI:10.3109/09513590.2013.859668] [PMID]
12. Khan MS, Shaikh A, Ratnani R. Ultrasonography and Doppler study to predict uterine receptivity in infertile patients undergoing embryo transfer. J Obstet Gynecol India 2016; 66 (Suppl.): 377-382. [DOI:10.1007/s13224-015-0742-5] [PMID] [PMCID]
13. Adibi A, Khadem M, Mardanian F, Hovsepian S. Uterine and arcuate arteries blood flow for predicting of ongoing pregnancy in in vitro fertilization. J Res Med Sci 2015; 20: 879-884. [DOI:10.4103/1735-1995.170622] [PMID] [PMCID]
14. Prasad S, Goyal R, Kumar Y, Nayar P, Hajela S, Kumaran A, et al. The relationship between uterine artery two-dimensional color Doppler measurement and pregnancy outcome: A prospective observational study. J Reprod Infertil 2017; 18: 251-256.
15. Ivanovski M, Damcevski N, Radevska B, Doicev G. Assessment of uterine artery and arcuate artery blood flow by transvaginal color Doppler ultrasound on the day of human chorionic gonadotropin administration as predictors of pregnancy in an in vitro fertilization program. Akush Ginekol (Sofiia) 2012; 51: 55-60.
16. Zollner U, Specketer MT, Zollner KP, Dietl J. Uterine artery blood flow in the periimplantation period in embryo transfer cycles. Asian Pac J Reprod 2012; 1: 177-182. [DOI:10.1016/S2305-0500(13)60073-1]
17. Abdel Kader M, Abdelmeged A, Mahran A, Abu Samra MF, Bahaa H. The usefulness of endometrial thickness, morphology and vasculature by 2D Doppler ultrasound in prediction of pregnancy in IVF/ICSI cycles. Egypt J Radiol Nuclear Med 2016; 47: 341-346. [DOI:10.1016/j.ejrnm.2015.08.014]
18. Nandi A, Martins WP, Jayaprakasan K, Clewes JS, Campbell BK, Raine-Fenning NJ. Assessment of endometrial and subendometrial blood flow in women undergoing frozen embryo transfer cycles. Reprod BioMed Online 2014; 28: 343-351. [DOI:10.1016/j.rbmo.2013.11.004] [PMID]
19. Mayer RB, Ebner T, Weiss C, Allerstorfer C, Altmann R, Oppelt P, et al. The role of endometrial volume and endometrial and subendometrial vascularization parameters in a frozen embryo transfer cycle. Reprod Sci 2019; 26: 1013-1018. [DOI:10.1177/1933719118804421] [PMID]
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