جمعه 31 مرداد 1404
[Archive]
دوره 19، شماره 5 - ( 3-1400 )
جلد 19 شماره 5 صفحات 120-120 |
برگشت به فهرست نسخه ها
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Vafaei Sh, Motejaded F, Ebrahimzadeh-bideskan A. O-19 Protective effect of crocin on electromagnetic field-induced testicular damage and heat shock protein A2 expression in male BALB/c mice. IJRM 2021; 19 (5) :120-120
URL: http://ijrm.ir/article-1-2951-fa.html
URL: http://ijrm.ir/article-1-2951-fa.html
O-19 Protective effect of crocin on electromagnetic field-induced testicular damage and heat shock protein A2 expression in male BALB/c mice. International Journal of Reproductive BioMedicine. 1400; 19 (5) :120-120
چکیده: (312 مشاهده)
Background: Exposure to electromagnetic fields (EMF) emitted from mobile phones may cause a deleterious effect on human health and may affect the male reproductive system. Crocin, a carotenoid isolated from Crocus Sativus L. (Saffron), is a phar macologically active component of saffron.
Objective: This study was conducted to investigate the protective effect of crocin on the male reproductive system of 60 day old mice after EMF exposure.
Materials and Methods: Twenty-four male BALB/c mice were randomly divided into 4 groups: 1) electromagnetic (EM) group (2100 MHZ); 2) Crocin (Cr) group (50 mg/kg); 3) Em+Cr group (2100 MHZ+50 mg/kg), and 4) Control group. Sperm parameters (count, and abnormal percent), testis weight index, testis volume, seminiferous tubule diameter, germinal epithelium thickness, luteinizing hormone, follicle-stimulating hormone and testosterone serum level, testicular Heat shock protein A2 (HspA2) immunoreactivity, and apoptosis were evaluated.
Results: HspA2 immunoreactivity, apoptosis in the germinal epithelium and abnormal sperm were increased in EM group compared with the control group (p < 0.05). Sperm count, luteinizing hormone, and testosterone serum level were decreased in the EM group compared with the control group (p < 0.05). These parameters were improved in the EM+Cr group compared with EM group significantly (p < 0.05).
Conclusion: Our findings revealed that EMF exposure leads to harmful impressions on the male reproductive system, while crocin can attenuate EMF-induced destructive effects.
Objective: This study was conducted to investigate the protective effect of crocin on the male reproductive system of 60 day old mice after EMF exposure.
Materials and Methods: Twenty-four male BALB/c mice were randomly divided into 4 groups: 1) electromagnetic (EM) group (2100 MHZ); 2) Crocin (Cr) group (50 mg/kg); 3) Em+Cr group (2100 MHZ+50 mg/kg), and 4) Control group. Sperm parameters (count, and abnormal percent), testis weight index, testis volume, seminiferous tubule diameter, germinal epithelium thickness, luteinizing hormone, follicle-stimulating hormone and testosterone serum level, testicular Heat shock protein A2 (HspA2) immunoreactivity, and apoptosis were evaluated.
Results: HspA2 immunoreactivity, apoptosis in the germinal epithelium and abnormal sperm were increased in EM group compared with the control group (p < 0.05). Sperm count, luteinizing hormone, and testosterone serum level were decreased in the EM group compared with the control group (p < 0.05). These parameters were improved in the EM+Cr group compared with EM group significantly (p < 0.05).
Conclusion: Our findings revealed that EMF exposure leads to harmful impressions on the male reproductive system, while crocin can attenuate EMF-induced destructive effects.
نوع مطالعه: Congress Abstract |
| بازنشر اطلاعات | |
 |
این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است. |
