پنجشنبه 30 مرداد 1404
[Archive]
دوره 19، شماره 5 - ( 3-1400 )
جلد 19 شماره 5 صفحات 274-274 |
برگشت به فهرست نسخه ها
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Ghanabri E, Khazaei F, Niromand E, Khazaei M. P-107
Prosopis farcta improves histopathological disorders and reduces oxidative stress of testicular tissue in diabetic rats. IJRM 2021; 19 (5) :274-274
URL: http://ijrm.ir/article-1-3018-fa.html
URL: http://ijrm.ir/article-1-3018-fa.html
P-107
Prosopis farcta improves histopathological disorders and reduces oxidative stress of testicular tissue in diabetic rats. International Journal of Reproductive BioMedicine. 1400; 19 (5) :274-274
چکیده: (335 مشاهده)
Background: Prosopis farcta (PF) has antioxidant effects and might be effective in avoiding damaging effects of diabetes on the testicular tissue.
Objective: This study purposes to examine the effect of PF on oxidative stress and the structure of testis in diabetic rats.
Materials and Methods: 32 male adult Wistar rats were randomly divided into control, PF, diabetic and diabetic/PF. Streptozotocin was administered intraperitoneally to induce diabetes mellitus in rats. PF group and PF-treated diabetic group received intraperitoneally 300 mg/kg extract of PF for 30 days. At the end of the study, the rats were weighed and dissected. Then, oxidative stress and histopathology of testis were examined.
Results: The level of malondialdehyde in diabetic rats treated with PF decreased in compared with diabetic group (p = 0.001), although PF extract increased the level of superoxide dismutase in the diabetic group (373.9 ± 16.6) (p < 0.001). Moreover, PF decreased testicular damage caused by diabetes mellitus.
Conclusion: Hydroalcoholic extract of PF improves testicular tissue structure in diabetic rats via decreasing oxidative stress.
Key words: Testis, Rat, Prosopis farcta.
Objective: This study purposes to examine the effect of PF on oxidative stress and the structure of testis in diabetic rats.
Materials and Methods: 32 male adult Wistar rats were randomly divided into control, PF, diabetic and diabetic/PF. Streptozotocin was administered intraperitoneally to induce diabetes mellitus in rats. PF group and PF-treated diabetic group received intraperitoneally 300 mg/kg extract of PF for 30 days. At the end of the study, the rats were weighed and dissected. Then, oxidative stress and histopathology of testis were examined.
Results: The level of malondialdehyde in diabetic rats treated with PF decreased in compared with diabetic group (p = 0.001), although PF extract increased the level of superoxide dismutase in the diabetic group (373.9 ± 16.6) (p < 0.001). Moreover, PF decreased testicular damage caused by diabetes mellitus.
Conclusion: Hydroalcoholic extract of PF improves testicular tissue structure in diabetic rats via decreasing oxidative stress.
Key words: Testis, Rat, Prosopis farcta.
نوع مطالعه: Congress Abstract |
| بازنشر اطلاعات | |
 |
این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است. |
