Volume 10, Issue 6 (4-2012)                   IJRM 2012, 10(6): 567-570 | Back to browse issues page

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Kara M, Aydin T, Turktekin N, S K. Efficacy of the local endometrial injury in patients who had previous failed IVF-ICSI outcome. IJRM 2012; 10 (6) :567-570
URL: http://ijrm.ir/article-1-319-en.html
1- Department of Obstetrics and Gynecology, Bozok University, Medical Faculty, Yozgat, Turkey , mustafa.kara@bozok.edu.tr
2- Department of Obstetrics and Gynecology, Kayseri In vitro Fertilization Center, Kayseri, Turkey
3- Department of Nuclear Medicine, Bozok University Medical Faculty, Yozgat, Turkey
Abstract:   (2497 Views)
Background: The latest studies reported that local endometrial injury is a useful method to improve the success of IVF-ICSI outcome.
Objective: To assess whether local endometrial injury occurred by Pipelle in the spontaneous cycle could improve implantation rate, cleavage rate, and pregnancy outcome in the subsequent IVF-ICSI cycle in patients who had recurrent IVF failure.
Materials and Methods: An endometrial biopsy was performed on day 21st in 41 patients as intervention group in this retrospective cross-sectional study. The control group contained 42 women.
Results: Implantation rate was 22.5% and 10.5% in intervention and control group, respectively and this difference was found to be statistically significant (p=001). Pregnancy rate was 43.9% in the intervention group and this parameter was significantly lower in control group (21.4%) (p=0.03).
Conclusion: Local endometrial injury in the nontransfer cycle increases the implantation rate and pregnancy rate in the subsequent IVF-ICSI cycle in patients who had previous failed IVF-ICSI outcome.
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Type of Study: Original Article |

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