International Journal of
Reproductive Biomedicine
Thu, Aug 14, 2025
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Volume 23, Issue 5 (May 2025 2025)
IJRM 2025, 23(5): 383-396 |
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Aringazina R, Zholdassova N, Berdesheva G, Nurgaliyeva Z, Kurmanalina G, Zhanalina B et al . Metabolic syndrome in reproductive age: A cross-sectional study. IJRM 2025; 23 (5) :383-396
URL: http://ijrm.ir/article-1-3321-en.html
URL: http://ijrm.ir/article-1-3321-en.html
Raisa Aringazina *1 
, Nurgul Zholdassova2 , Gulshara Berdesheva3 , Zhansulu Nurgaliyeva4 , Gulnara Kurmanalina5 , Bakhyt Zhanalina6 , Zoia Sharlovych7
, Nurgul Zholdassova2 , Gulshara Berdesheva3 , Zhansulu Nurgaliyeva4 , Gulnara Kurmanalina5 , Bakhyt Zhanalina6 , Zoia Sharlovych7
1- Department of Internal Diseases no. 1, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan. , omnid@zkgmu.kz
2- Department of Therapeutic and Orthopedic Dentistry, Khoja Akhmet Yassawi International University, Turkestan, the Republic of Kazakhstan.
3- Department of General Hygiene, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan.
4- Department of Pharmacology, Kazakhstan-Russian Medical University, Almaty, the Republic of Kazakhstan.
5- Department of Internal Diseases no. 2, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan.
6- Department of Surgical and Pediatric Dentistry, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan.
7- Department of Pedagogy, International University of Applied Sciences in Lomza, Lomza, Poland. & Department of Professional and Pedagogical, Special Education, Andragogy and Management, Educational and Research Institute of Pedagogics, Zhytomyr Ivan Franko State University, Zhytomyr, Ukraine.
2- Department of Therapeutic and Orthopedic Dentistry, Khoja Akhmet Yassawi International University, Turkestan, the Republic of Kazakhstan.
3- Department of General Hygiene, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan.
4- Department of Pharmacology, Kazakhstan-Russian Medical University, Almaty, the Republic of Kazakhstan.
5- Department of Internal Diseases no. 2, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan.
6- Department of Surgical and Pediatric Dentistry, West Kazakhstan Marat Ospanov Medical University, Aktobe, the Republic of Kazakhstan.
7- Department of Pedagogy, International University of Applied Sciences in Lomza, Lomza, Poland. & Department of Professional and Pedagogical, Special Education, Andragogy and Management, Educational and Research Institute of Pedagogics, Zhytomyr Ivan Franko State University, Zhytomyr, Ukraine.
Abstract: (201 Views)
Background: Obesity and metabolic syndrome (MetS), as components of excess body weight, have reached global epidemic levels.
Objective: The study aimed to investigate the features of the MetS course in men and women of reproductive age.
Materials and Methods: This cross-sectional study was conducted with 140 participants aged between 35 and 49 yr at City Polyclinics No. 1, 3, and 4, Aktobe, Kazakhstan from March 2016-2019. Participants were divided into 2 subgroups based on diagnosis of MetS. The case group (with MetS), and the control group (without MetS) (n = 70/each consisted of 40 women and 30 men). Anthropometric, instrumental, and laboratory methods were used to confirm the diagnosis of MetS and determine its features in both groups.
Results: The results showed an increase in the uric acid level in the blood to 431.00 ± 66.37 μmol/L and 5.47 ± 0.90 mol/day in the urine. Dyslipidemia was also noted in the case group of individuals with high-density lipoprotein levels of 1.22 ± 0.27 mmol/L vs. 1.32 ± 0.47 mmol/L in the control group. The testosterone level was 16.4 ± 3.04 nmol/L in the case group and 20.3 ± 5.6 nmol/L in the control. The difference in testosterone level was found to be statistically significant (p ˂ 0.01).
Conclusion: The analysis of sex hormone levels did not reveal any stable trends that could be considered diagnostic. That may indicate a correlation with the reproductive age characteristics of the examined individuals (men and women): significant differences between hormone levels were fixed in the case and control groups.
Objective: The study aimed to investigate the features of the MetS course in men and women of reproductive age.
Materials and Methods: This cross-sectional study was conducted with 140 participants aged between 35 and 49 yr at City Polyclinics No. 1, 3, and 4, Aktobe, Kazakhstan from March 2016-2019. Participants were divided into 2 subgroups based on diagnosis of MetS. The case group (with MetS), and the control group (without MetS) (n = 70/each consisted of 40 women and 30 men). Anthropometric, instrumental, and laboratory methods were used to confirm the diagnosis of MetS and determine its features in both groups.
Results: The results showed an increase in the uric acid level in the blood to 431.00 ± 66.37 μmol/L and 5.47 ± 0.90 mol/day in the urine. Dyslipidemia was also noted in the case group of individuals with high-density lipoprotein levels of 1.22 ± 0.27 mmol/L vs. 1.32 ± 0.47 mmol/L in the control group. The testosterone level was 16.4 ± 3.04 nmol/L in the case group and 20.3 ± 5.6 nmol/L in the control. The difference in testosterone level was found to be statistically significant (p ˂ 0.01).
Conclusion: The analysis of sex hormone levels did not reveal any stable trends that could be considered diagnostic. That may indicate a correlation with the reproductive age characteristics of the examined individuals (men and women): significant differences between hormone levels were fixed in the case and control groups.
Type of Study: Original Article |
Subject:
Reproductive Physiology
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