Volume 11, Issue 2 (4-2013)                   IJRM 2013, 11(2): 133-0 | Back to browse issues page

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Eftekhar M, Rahmani E, Mohammadian F. Comparison of pregnancy outcome in half-dose Triptorelin and short-acting Decapeptyl in long protocol in ART cycles: A randomized clinical trial. IJRM 2013; 11 (2) :133-0
URL: http://ijrm.ir/article-1-384-en.html
Comparison of pregnancy outcome in half-dose Triptorelin and short-acting Decapeptyl in long protocol in ART cycles: A randomized clinical trial
Maryam Eftekhar * 1, Elham Rahmani2 , Farnaz Mohammadian3
1- Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , rahmani@bpums.ac.ir
2- Department of Obstetrics and Gynecology, Bushehr University of Medical Sciences, Bushehr, Iran
3- Department of Obstetrics and Gynecology, Zanjan University of Medical Sciences, Zanjan, Iran
Abstract:   (3354 Views)
Background: Gonadotrophin-releasing hormone (GnRH) agonist is used for controlling ovarian stimulation in assisted reproductive technology (ART) cycles which has some benefits.
Objective: To compare the efficacy of two different formulations of GnRH agonist: short-acting and long-acting, for ART protocols.
Materials and Methods: In a prospective randomized study, one hundred women who underwent ART cycles were randomly divided into two groups. In group I, the patients received one single injection of 1.87 mg Triptorelin in previous mid-luteal phase. In group II, Decapeptyl 0.1 mg per day started from previous mid-luteal phase. Pregnancy outcome in in vitro fertilization (IVF) cycle was compared between two groups.
Results: There were no statistically significant differences in the number of retrieved oocyte (p=0.545), fertilization (p=0.876), implantation (p=0.716) and pregnancy rate (p=0.727) between the two groups.
Conclusion: There were not any advantages in IVF outcome between half-dose long-acting and short-acting GnRH agonist groups in ART cycle.
Keywords: Infertility, GnRH agonist, In vitro fertilization, Pregnancy outcome, Decapeptyl.
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Type of Study: Original Article |
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