Volume 14, Issue 9 (9-2016)                   IJRM 2016, 14(9): 603-606 | Back to browse issues page

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Hasanzadeh M, Vahid Roodsari F, Ahmadi S, Gavedan Mehr M, Azadeh T. Fertility sparing surgery in gestational trophoblastic neoplasia: A report of 4 cases. IJRM 2016; 14 (9) :603-606
URL: http://ijrm.ir/article-1-779-en.html
Fertility sparing surgery in gestational trophoblastic neoplasia: A report of 4 cases
Malihe Hasanzadeh1 , Ftemeh Vahid Roodsari1 , Shahnaz Ahmadi * 2, Masoumeh Gavedan Mehr3 , Tabari Azadeh3
1- Department of Gynecologic Oncology, Women Health Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2- Department of Obstetrics and Gynecology, Shahid Akbarabadi Hospital, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran , Ahmadishahnaz2005 @yahoo.com
3- Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:   (2338 Views)
Background: Gestational trophoblastic neoplasia (GTN) is a curable disease thatinvolves the development of malignant tumor in the woman after a normal or molarpregnancy. The position of surgery in GTN is not properly specified and is changingdue to new chemotherapy protocols. However, the role of surgery is highlighted inchemotherapy-resistant GTN. Other indications of surgery in trophoblastic diseasesare drug toxicity and uterine perforation. Based on the fact that most women incertain age tend to preserve fertility, this study reported 4 cases of successfultreatment after fertility sparing surgery.
Case: A hospital-based case-report study was carried out to investigate the role ofsurgery in 4 patients with GTN. In this study, acute complications, such as intraabdominalbleeding and liver dysfunction due to chemotherapy occurred in somepatients. Surgery was performed and all cases underwent localized tumor removalwhile preserving the uterus. No hysterectomy surgery was performed.
Conclusion: Surgery is supposed in specific cases of GTN, who desire preservingfertility.
Keywords: GTT, Fertility, Surgery, Chemotherapy
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Type of Study: Original Article |
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